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Neuralox Product Research

Neuralox Advanced Memory Formula is formulated using leading research on Memory boosting neural nutrients. Each of Neuralox’s 3 systems is designed to support specific needs of your brain.

Neuralox's 3-Complex System - Triple Action

(1) Mind Protect System helps increase blood, nutrient, and oxygen delivery to the brain, while a powerful blend of antioxidants and anti inflammatory agents protects your mind from oxidative stress, free radical damage and premature cellular aging.

Alpha Lipoic acid – The Universal antioxidant since it is both fat- and water- soluble, unlike other antioxidants, It can cross the blood-brain barrier and hence, protects the brain and nerve tissue from oxidative damage. ALA is also consider one of the most effective compounds in fighting premature aging at the cellular level.

Bacopa monninera – A powerful antioxidant (Saponin) and anti-inflammatory herb that amplifies the effects of the body’s natural neural protective compounds and antioxidants.

Vinpocetine - Derived from periwinkle flower leaves, vinpocetine boosts memory function. In scientific tests and clinical trials, vinpocetine, was shown to improve blood circulation and nutrient delivery to the brain. Another amazing property of vinpocetine is that it not only aids memory enhancement, it actually repairs damage to the brain, protect the brain from breakdown. Increased blood and nutrient delivery to the brain not only improves memory function but also has shown benefit in hearing and eye sight.

(2) Brain Nourish System provides you with 6 essential vitamins and nutrients that your brain requires to protect, heal and function at optimum levels.

DHA - One of the major building blocks of the brain, the omega-3 fatty acid docosahexaenoic acid (DHA) is critical for optimal brain health and function at all ages of life. Researchers are now finding that DHA provides brain-boosting benefits in infants and aging adults.

Vitamin B6, B12, Folic acid - Complex B vitamins improve memory, any studies that have been conducted revealed that cognitive functions improve in time, if a treatment based on folate, vitamin B12 and B6 is followed. People who take these vitamins seem to process information at greater speeds. Complex B vitamins improve memory by reducing the stress and by protecting the nerves. It is a known fact that the deficit of vitamin B6 is usually correlated to nerve damage. When supplementing with vitamin B6, people can also reduce the depression, which is a main factor of memory loss. This vitamin regulates the GABA and serotonin neurotransmitters, which are tightly related to the levels of stress, depression and anxiety.

Phosphatidylserine – Phosphatidylserine is a phospholipid that is vital to your brain cells. Phospholipids are molecules containing both amino and fatty acids found in every cell membrane within our bodies. Actually, phosphatidylserine is universally present in living things from the most simple to the most complex. Phosphatidylserine has many known functions throughout all of our tissues and organs, but is most important as the key building block for the billions of cells that make up our brain.

Pantothenic acid (Vitamin B5) - Also a member of the B vitamin family, Vitamin B5 is a key precursor for the production of the neurotransmitter Acetyl Choline.

(3) AC Memory Maximizer System is developed to support your brain's healthy Acetyl Choline levels, the single most important factor for healthy memory and cognitive function.

Choline / Phosphocholine (Lecithin) - Choline and Phosphocholine are precursor for the production of neuro transmitters and are essential for cellular communication. The compound Choline is also required for the production of the neurotransmitter Acetyl Choline.

DMAE - Enhances brain activity as it readily moves through the brain-blood barrier then converting into Choline, it is believed that DMAE is effective in aiding brain function by stimulating the production of neurotransmitters such as Acetyl Choline. Dr Nicholas Perricone, renowned antiaging doctor, writes "Taking DMAE as a supplement has shown to increase cognitive function by improving memory and problem-solving ability. It has been shown to assist improvement in such disorders as attention deficit disorder (ADD)"

Acetyl L-carnitine – A power antioxidant that is key to energy production and neural protection. During the processing of ALC, the Acetyl group is released within the blood/brain to form a key component in the production for Acetyl Choline

Huperzine A – A natural derivative from Club moss, which is key to protecting your Acetyl Choline levels. Huperzine A is the only substance known to cross the blood-brain barrier and inhibit the action of the enzyme, acetylcholinesterase. Acetylcholinesterase acts by breaking down the neurotransmitter acetylcholine, by inhibiting this activity, Huperzine A directly leads to an increase in the concentration of the neurotransmitter acetylcholine.

The formula is developed to have a cumulative benefit on your overall brain health. Each system within Neuralox will begin delivering specific neural nutrients to your body and brain right away. Do not feel surprised if you begin feeling overall body benefits beyond just memory and mood, as Neuralox will elevate your levels of vitamins, anti oxidants and anti inflammatory nutrients.

An extra pill is okay - Neuralox designed for when your brain needs it most.

In times of high stress and memory demand it is safe to increase the dosage to 3 tablets daily. So when you have a stressful event such as a major deadline, an examination, you now have the support your need. Even during the holidays when you are strained and tired Neuralox can help, when you feel you have the blues and are mentally drained an extra tablet a day will give you added mental and mood support.

 

Clinical Research on the Key ingredients in Neuralox Advanced Memory Formula

Mind Protect System

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Vas A, Gulyas B, Szabo Z, et al. Clinical and non-clinical investigations using positron emission tomography, near infrared spectroscopy and transcranial Doppler methods on the neuroprotective drug vinpocetine: a summary of evidences. J Neurol Sci. 2002 Nov 15;203-204:259-62.

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Pereira C, Agostinho P, Oliveira CR. Vinpocetine attenuates the metabolic dysfunction induced by amyloid beta-peptides in PC12 cells. Free Radic Res. 2000 Nov;33(5):497-506.

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Smith AR, Shenvi SV, Widlansky M, Suh JH, Hagen TM. Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress. Curr Med Chem. 2004;11(9):1135-1146.

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A randomized, double-blind, placebo-controlled trial of deprenyl and thioctic acid in human immunodeficiency virus-associated cognitive impairment. Dana Consortium on the Therapy of HIV Dementia and Related Cognitive Disorders. Neurology. 1998; 50(3):645-651.

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Russo A, Izzo AA, Borrelli F, Renis M, Vanella A. Free radical scavenging capacity and protective effect of Bacopa monniera L. on DNA damage. Phytother Res. 2003 Sep; 17(8): 870-5.

Brain Nourish System

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Deijen JB, van der Beek EJ, Orlebeke JF, van den Berg H. Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort. Psychopharmacology (Berl). 1992; 109(4):489-496.

Bryan J, Calvaresi E, Hughes D. Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages. J Nutr. 2002;132(6):1345-1356.

Balk EM, Raman G, Tatsioni A, Chung M, Lau J, Rosenberg IH. Vitamin B6, B12, and folic acid supplementation and cognitive function: a systematic review of randomized trials. Arch Intern Med. 2007;167(1):21-30.

Talbott MC, Miller LT, Kerkvliet NI. Pyridoxine supplementation: effect on lymphocyte responses in elderly persons. Am J Clin Nutr. 1987; 46(4):659-664.

Ishrat T, Hoda MN, Khan MB, Yousuf S, Ahmad M, Khan MM, Ahmad A, Islam F. Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer’s type (SDAT). Eur Neuropsychopharmacol. 2009 Mar 27. Published Online Ahead of Print

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Satoskar RR, Shah SJ, Shenoy SG. Evaluation of anti-inflammatory property of curcumin in patients with post operative inflammation. Int J Clin Pharmacol Ther Toxicol 1986;24:651-4.

Ebly EM, Schaefer JP, Campbell NR, Hogan DB. Folate status, vascular disease and cognition in elderly Canadians. Age Ageing. 1998; 27(4):485-491.

Luchsinger JA, Tang MX, Miller J, Green R, Mayeux R. Relation of higher folate intake to lower risk of Alzheimer disease in the elderly. Arch Neurol. 2007;64(1):86-92.

Morris MC, Evans DA, Schneider JA, Tangney CC, Bienias JL, Aggarwal NT. Dietary folate and vitamins B-12 and B-6 not associated with incident Alzheimer's disease. J Alzheimers Dis. 2006;9(4):435-443.

Morris MC, Evans DA, Bienias JL, et al. Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older persons. Arch Neurol. 2005;62(4):641-645.

Solini A, Santini E, Ferrannini E. Effect of short-term folic acid supplementation on insulin sensitivity and inflammatory markers in overweight subjects. Int J Obes (Lond). 2006 Aug;30(8):1197-202.

Wang HX, Wahlin A, Basun H, Fastbom J, Winblad B, Fratiglioni L. Vitamin B(12) and folate in relation to the development of Alzheimer's disease. Neurology. 2001; 56(9):1188-1194.

Nourhashemi F, Gillette-Guyonnet S, Andrieu S, et al. Alzheimer disease: protective factors. Am J Clin Nutr. 2000; 71(2):643S-649S.

Eussen SJ, de Groot LC, Joosten LW, et al. Effect of oral vitamin B-12 with or without folic acid on cognitive function in older people with mild vitamin B-12 deficiency: a randomized, placebo-controlled trial. Am J Clin Nutr. 2006; 84(2):361-370.

Penninx BW, Guralnik JM, Ferrucci L, Fried LP, Allen RH, Stabler SP. Vitamin B(12) deficiency and depression in physically disabled older women: epidemiologic evidence from the Women's Health and Aging Study. Am J Psychiatry. 2000; 157(5):715-721.

Tahiliani, A.G. & Beinlich, C.J. (1991) Pantothenic acid in health and disease. Vitamins and Hormones 46: 165-228.

Slyshenkov, VS, Dymkowska, D, Wojtczak, L. (2004). Pantothenic acid and patothenol increase biosynthesis of glutathione by boosting cell energetics. FEBS Lett. 569(1-3):169-72.

Gaddi A, Descovich GC, Noseda G, et al. Controlled evaluation of pantethine, a natural hypolipidemic compound, in patients with different forms of hyperlipoproteinemia. Atherosclerosis. 1984;50(1):73-83.

Lukiw WJ, Cui JG, Marcheselli VL, Bodker M, Botkjaer A, Gotlinger K, Serhan CN, Bazan NG. (2005 Oct). "A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease". J Clin Invest. 115(10): 2774–83.

McNamara RK, Hahn CG, Jandacek R, et al. (2007). "Selective deficits in the omega-3 fatty acid docosahexaenoic acid in the postmortem orbitofrontal cortex of patients with major depressive disorder". Biol. Psychiatry 62 (1): 17–24.

Kyle DJ, Schaefer E, Patton G, Beiser A. Low serum docosahexaenoic acid is a significant risk factor for Alzheimer's dementia. Lipids. 1999;34 Suppl:S245.

Tully AM, Roche HM, Doyle R, et al. Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case-control study. Br J Nutr. 2003; 89(4):483-489.

Wurtman, R.J. Synapse formation and cognitive brain development: effect of docosahexaenoic acid and other dietary constituents. Metabolism. 2008, 57 Suppl 2:S6-10.

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AC Memory Maximizer

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Wang, Z.F., Wang, J., Zhang, H.Y. and Tang, X.C. Huperzine A exhibits anti-inflammatory and neuroprotective effects in a rat model of transient focal cerebral ischemia. J Neurochem. 106(4):1594-603.

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